Italian Penicillin Soup is a comforting dish that has been a staple in many Italian households, especially during the colder months or when feeling under the weather. This hearty soup is not only delicious but also packed with healing ingredients, making it the perfect remedy for colds and flu. With tender chicken, vibrant vegetables, and a medley of aromatic herbs, it’s designed to nourish your body and uplift your spirit.
Why You’ll Love This Italian Penicillin Soup
This Italian penicillin soup recipe offers numerous benefits. First, it’s loaded with nutrients from fresh vegetables like carrots and spinach, promoting overall health. Second, the chicken provides a rich source of protein, essential for recovery. Third, the combination of herbs—like basil and oregano—adds flavor while also offering anti-inflammatory properties. Fourth, this soup is easy to make, perfect for busy weeknights. Fifth, it’s a comforting dish that warms you from the inside out, ideal for those chilly evenings. Lastly, it’s gluten-free, making it suitable for various dietary needs. These Italian medicinal soup benefits make it a must-try!

Ingredients for Italian Penicillin Soup
Gather these items:
- 1 lb chicken breast or chicken thighs (boneless, skinless)
- 2 tablespoons olive oil
- 1 large onion, chopped
- 2 carrots, sliced
- 2 celery stalks, chopped
- 4 cloves garlic, minced
- 1 zucchini, diced
- 1 cup spinach (or kale), chopped
- 1 can (14.5 oz) diced tomatoes, with juice
- 6 cups chicken broth
- 1 teaspoon dried basil
- 1 teaspoon dried oregano
- 1/2 teaspoon dried thyme
- 1 bay leaf
- Salt and pepper, to taste
- 1 cup small pasta (optional, such as ditalini, orzo, or small shells)
- Fresh parsley or basil, for garnish
- Parmesan cheese, for serving (optional)
How to Make Italian Penicillin Soup Step-by-Step
- Step 1: Heat 1 tablespoon olive oil in a large pot over medium heat. Season the chicken with salt and pepper and cook for about 5–7 minutes per side, until browned and cooked through. Once cooked, remove the chicken from the pot and set it aside to cool. Shred the chicken into bite-sized pieces.
- Step 2: In the same pot, add 2 tablespoons olive oil. Add the onion, carrots, and celery. Sauté for about 5–7 minutes until softened. Add minced garlic and sauté for another 1–2 minutes until fragrant.
- Step 3: Add diced tomatoes (with juice) and chicken broth to the pot. Stir in basil, oregano, thyme, and bay leaf. Bring the mixture to a simmer, reduce heat to low, and let it cook for 15–20 minutes.
- Step 4: Add shredded chicken and zucchini to the pot. Simmer for another 10–12 minutes until zucchini is tender.
- Step 5: If adding pasta, stir it in and cook according to package instructions. Add spinach during the last 2–3 minutes of cooking.
- Step 6: Taste the soup and adjust seasoning with salt and pepper. Add a squeeze of lemon juice or a dash of hot sauce for extra flavor.
- Step 7: Ladle the soup into bowls and garnish with fresh parsley or basil. If desired, sprinkle with Parmesan cheese before serving.
Pro Tips for the Best Italian Penicillin Soup
Keep these in mind:
- This soup is great for meal prep and can be stored in the fridge for up to 3 days.
- You can freeze leftovers for up to 2 months.
- For a more intense flavor, consider using homemade chicken broth.
- Adjust the herbs according to your taste; fresh herbs can elevate the flavor.

Best Ways to Serve Italian Penicillin Soup
For a complete meal, consider serving this Italian chicken soup for healing with crusty bread or a side salad. It pairs well with a sprinkle of grated Parmesan cheese and a drizzle of olive oil for added richness. You can also make it heartier by adding a side of garlic bread or a fresh Italian loaf.
How to Store and Reheat Italian Penicillin Soup
This soup is perfect for meal prep. You can store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, simply warm it on the stovetop or in the microwave until heated through. If you freeze it, make sure to leave some space in the container as the soup will expand when frozen.
Frequently Asked Questions About Italian Penicillin Soup
What is Italian penicillin soup?
Italian Penicillin Soup is a nutritious and comforting chicken soup, often enjoyed during cold and flu season. It’s filled with healing ingredients designed to boost immunity.
Can I make Italian penicillin soup ahead of time?
Absolutely! This homemade Italian penicillin soup can be made ahead of time. It actually tastes better the next day as the flavors meld together.
How do I avoid common mistakes with Italian penicillin soup?
To avoid common mistakes, ensure you season your soup properly throughout the cooking process. Also, avoid overcooking the vegetables, which can lead to a mushy texture.
Variations of Italian Penicillin Soup You Can Try
Feel free to customize your soup! You can add other vegetables like bell peppers or peas for extra nutrition. For a vegan version, substitute chicken with chickpeas and use vegetable broth instead. You can also try different herbs and spices to create a unique flavor profile, making this a versatile Italian detox soup recipe.
For more delicious recipes, check out our recipe collection or try our Greek Lemon Chicken Soup for a refreshing twist. If you’re looking for a hearty option, our Incredible Chicken Parm Soup is a must-try!
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Healing Italian Penicillin Soup for Comfort and Recovery
- Total Time: 1 hour
- Yield: 6 servings 1x
- Diet: Gluten Free
Description
This Italian Penicillin Soup is packed with tender chicken, nutritious vegetables like carrots, celery, and spinach, and savory herbs. It’s the perfect comfort food to warm you up, and it’s filled with healing ingredients to nourish your body.
Ingredients
- 1 lb chicken breast or chicken thighs (boneless, skinless)
- 2 tablespoons olive oil
- 1 large onion, chopped
- 2 carrots, sliced
- 2 celery stalks, chopped
- 4 cloves garlic, minced
- 1 zucchini, diced
- 1 cup spinach (or kale), chopped
- 1 can (14.5 oz) diced tomatoes, with juice
- 6 cups chicken broth
- 1 teaspoon dried basil
- 1 teaspoon dried oregano
- 1/2 teaspoon dried thyme
- 1 bay leaf
- Salt and pepper, to taste
- 1 cup small pasta (optional, such as ditalini, orzo, or small shells)
- Fresh parsley or basil, for garnish
- Parmesan cheese, for serving (optional)
Instructions
- Heat 1 tablespoon olive oil in a large pot over medium heat. Season the chicken with salt and pepper and cook for about 5–7 minutes per side, until browned and cooked through. Once cooked, remove the chicken from the pot and set it aside to cool. Shred the chicken into bite-sized pieces.
- In the same pot, add 2 tablespoons olive oil. Add the onion, carrots, and celery. Sauté for about 5–7 minutes until softened. Add minced garlic and sauté for another 1–2 minutes until fragrant.
- Add diced tomatoes (with juice) and chicken broth to the pot. Stir in basil, oregano, thyme, and bay leaf. Bring the mixture to a simmer, reduce heat to low, and let it cook for 15–20 minutes.
- Add shredded chicken and zucchini to the pot. Simmer for another 10–12 minutes until zucchini is tender.
- If adding pasta, stir it in and cook according to package instructions. Add spinach during the last 2–3 minutes of cooking.
- Taste the soup and adjust seasoning with salt and pepper. Add a squeeze of lemon juice or a dash of hot sauce for extra flavor.
- Ladle the soup into bowls and garnish with fresh parsley or basil. If desired, sprinkle with Parmesan cheese before serving.
Notes
- This soup is great for meal prep and can be stored in the fridge for up to 3 days.
- You can freeze leftovers for up to 2 months.
- Prep Time: 15 minutes
- Cook Time: 45 minutes
- Category: Soup
- Method: Stovetop
- Cuisine: Italian
Nutrition
- Serving Size: 1 cup
- Calories: 210
- Sugar: 3g
- Sodium: 800mg
- Fat: 9g
- Saturated Fat: 1.5g
- Unsaturated Fat: 7g
- Trans Fat: 0g
- Carbohydrates: 20g
- Fiber: 3g
- Protein: 24g
- Cholesterol: 70mg








